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When someone gets infected with influenza, and gains some immunity, is that immunity just as good as getting it from a vaccine? WASHINGTON — Monkeys infected with a resurrected virus that was responsible for history’s deadliest epidemic have given scientists a better idea of how the 1918 Spanish flu attacked so quickly and relentlessly: by turning victims’ bodies against them. The fate of the monkeys was sealed within hours of their infections, Katze theorized. See today's front and back pages, download the newspaper, He reported that in thirteen studies of hospitalized women in the pandemic, the death rate ranged from 23% to 71%.

[94] Nevertheless, actions were taken. How can I allow bidirectional time travel in a deterministic block universe? [132] Tafari Makonnen (the future Haile Selassie, Emperor of Ethiopia) was one of the first Ethiopians who contracted influenza but survived. suffered no additional adverse economic effects due to implementing those measures,[170] when compared with cities that implemented measures late or not at all. (2007) reported that monkeys (Macaca fascicularis) infected with the recreated flu strain exhibited classic symptoms of the 1918 pandemic, and died from cytokine storms[213] – an overreaction of the immune system. This study randomly assigned older adults (65 – 82 years old) in Hong Kong to receive either a standard 4-component flu vaccine or one of three specially formulated flu vaccine options sometimes called “enhanced” vaccines.

site design / logo © 2020 Stack Exchange Inc; user contributions licensed under cc by-sa. [175], Despite the high morbidity and mortality rates that resulted from the epidemic, the Spanish flu began to fade from public awareness over the decades until the arrival of news about bird flu and other pandemics in the 1990s and 2000s.

[178], Additionally, the outbreak coincided with the deaths and media focus on the First World War.

Many children also had jobs, from delivering newspapers to helping on farms and even working in factories. In 1918, schools closed temporarily in response to a new flu virus. One hypothesis is that the virus strain originated at Fort Riley, Kansas, in viruses in poultry and swine which the fort bred for food; the soldiers were then sent from Fort Riley around the world, where they spread the disease.

Thanks for contributing an answer to Biology Stack Exchange! [214], On 16 September 2008, the body of British politician and diplomat Sir Mark Sykes was exhumed to study the RNA of the flu virus in efforts to understand the genetic structure of modern H5N1 bird flu. The first wave had resembled typical flu epidemics; those most at risk were the sick and elderly, while younger, healthier people recovered easily. The general population was familiar with patterns of pandemic disease in the late 19th and early 20th centuries: typhoid, yellow fever, diphtheria and cholera all occurred near the same time. [222][223] Worobey traced recent references to that article to family members who had retained slides that Rolland had prepared during that time.

[211][212], On 18 January 2007, Kobasa et al.

However, this 1991 study was criticized by later studies due to flawed methodology, and newer studies have published estimates of a far lower mortality rate in China. Britain was still at war when the virus claimed its first recorded victim, in May 1918. To practice penmanship or work on math problems, students wrote with chalk or charcoal on a slate — a piece of wood with special coating.

If this virus was still extant, wouldn't we see small deadly flu epidemics in various places over the last 100 years?

One can hardly believe that after infecting half a billion people, the virus was contained in any sense of the word. Immune System. Many strains of influenza circulated before 1918, but we don’t know much about them because we don’t have samples. Lasting from February 1918 to April 1920, it infected 500 million people—about a third of the world's population at the time—in four successive waves.

Why?

I thought that even if an answer, Another clarification: I know there is no reason why the Spanish Flu had to remain particularly common. Why didn't we see some small epidemics continue to circulate the globe infecting the yet-uninfected as well as newly born people for many years - potentially until today? According to "Harrison’s Principles of Internal Medicine," cytokines are a kind of chemical distress call issued by T-cells, B-cells and natural killer cells of the immune systems in response to influenza infection.

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