All subjects, or their representatives, gave written informed consent prior to enrolment according to Vietnamese Ministry of Health policy and good clinical practice guidelines. This rare but serious reaction to a tetanus vaccine may begin 2 days to 4 weeks after you receive the vaccine, and could last up to many months.Becoming infected with tetanus is much more dangerous to your health than receiving this vaccine. However, not vaccinating the mother could be more harmful to the baby if the mother becomes infected with a disease that this vaccine could prevent.

Call your doctor for medical advice about side effects. In the case of a more severe illness with a fever or any type of infection, wait until you get better before receiving this vaccine.You may not be able to receive tetanus toxoid vaccine if you have ever received a similar vaccine that caused a life-threatening allergic reaction or a neurologic disorder or disease affecting the brain.Before you receive this vaccine, tell your healthcare provider if you have a bleeding or blood-clotting disorder, easy bruising or bleeding, a history of Guillain Barré syndrome, an allergy to latex rubber, a weak immune system, or if you are receiving treatments that can weaken the immune system (such as radiation, chemotherapy, or steroids).You should not receive a booster vaccine if you had a life threatening allergic reaction after the first shot.Keep track of any and all side effects you have after receiving this vaccine. This includes prescription, over-the-counter, vitamin, and herbal products. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor or nurse immediately if any of the following side effects occur:Some side effects may occur that usually do not need medical attention. This vaccine will not treat an active infection that has already developed in the body.The tetanus toxoid vaccine is used to help prevent this disease in adults and children who are at least 7 years old.Like any vaccine, the tetanus toxoid vaccine may not provide protection from disease in every person.You can still receive a vaccine if you have a minor cold. This is called localized tetanus. Neither Everyday Health nor its licensors endorse drugs, diagnose patients or recommend therapy. Muscle spasms can be strong enough to break a child’s spine or other bones. You will be kept in a dark, quiet room to prevent muscle spasms. This rare but serious reaction to a tetanus vaccine may begin 2 days to 4 weeks after you receive the vaccine, and could last up to many months. Muscle spasms are controlled with benzodiazepines, with magnesium sulphate and neuromuscular blocking agents as second-line agents following tracheostomy. Patients with tetanus may be particularly at risk of muscle wasting and poor outcome due to long periods in the ICU and prolonged use of mechanical ventilation and muscle relaxants. It can take months to recover fully from tetanus. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide,This PDF is available to Subscribers Only.For full access to this pdf, sign in to an existing account, or purchase an annual subscription.Search for other works by this author on:Centre for Tropical Medicine and Global Health, University of Oxford.Corresponding author: Telephone: +842839237954; E-mail:Mortality from tetanus between 1990 and 2015 :findings from the global burden of disease study 2015,Pharmacological management of tetanus :an evidence-based review,Semi-recumbent body position fails to prevent healthcare-associated pneumonia in Vietnamese patients with severe tetanus,Impact of improved vaccination programme and intensive care facilities on incidence and outcome of tetanus in southern Vietnam, 1993–2002,Long-term outcome in survivors of neonatal tetanus following specialist intensive care in Vietnam,Long-term outcomes and healthcare utilization following critical illness – a population-based study,Skeletal muscle predicts ventilator-free days, ICU-free days, and mortality in elderly ICU patients,Presence and severity of intensive care unit-acquired paresis at time of awakening are associated with increased intensive care unit and hospital mortality,Metabolic phenotype of skeletal muscle in early critical illness,Ultrasonography in the intensive care setting can be used to detect changes in the quality and quantity of muscle and is related to muscle strength and function.Neuromuscular blockade and skeletal muscle weakness in critically ill patients: time to rethink the evidence?Effect of 10 days of bed rest on skeletal muscle in healthy older adults,Paresis acquired in the intensive care unit: a prospective multicentre study,Predicting the clinical outcome of tetanus: the tetanus severity score,The timed “Up & Go”: a test of basic functional mobility in elderly persons,Baltimore City Medical Society Functional Evaluation: the Barthel Index,The MOS 36-item short-form health survey (SF-36).

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